Ovesse 1mg/g Vaginal Cream

What is Ovesse?

Ovesse 1mg cream is used to relieve vaginal dryness and irritation (vaginal atrophy) caused by hormonal changes during or after menopause. It provides the hormone estriol, a form of oestrogen, to alleviate these symptoms.

How does estriol work?

During and after menopause, the body's natural oestrogen levels decrease, leading to symptoms like vaginal dryness and irritation. Estriol helps to:

1. Stimulate Tissue Growth: Estriol promotes the growth and maintenance of the vaginal and urogenital tissues, which helps to restore their natural elasticity and thickness.
2. Increase Blood Flow: It enhances blood flow to the vaginal area, improving lubrication and reducing dryness and discomfort.
3. Maintain pH Balance: Estriol helps maintain the natural acidic pH of the vagina, which is essential for preventing infections and maintaining overall vaginal health.
4. Enhance Mucosal Function: By improving the health and function of the mucosal lining, estriol helps to alleviate symptoms of atrophy and irritation.

Overall, estriol works by replenishing oestrogen levels in the targeted area, thus mitigating the symptoms associated with decreased oestrogen production during menopause.

How long does estriol take to work?

Typically, when women begin using Estriol Cream for vaginal dryness, they apply it once daily for 2 to 3 weeks. Most women experience significant improvement in their condition within this period.

If you do not notice sufficient relief after 4 weeks, you should consult a doctor for further guidance.

How to use Ovesse

Ovesse comes in a pack together with a clear plastic applicator.

Use the applicator to apply the cream in the vagina. A good time to do this is before going to bed.

The applicator has a red ring marked on the body. Fill the applicator up to the red ring mark with Ovesse vaginal cream to get the correct dose.

1. Remove the cap from the tube and turn the cap upside down. Then use the sharp point to open the tube.
2. Screw the end of the applicator onto the tube.
3. Squeeze the tube to fill the applicator with the cream up to the red ring mark (the plunger will stop at the red ring mark).
4. Unscrew the applicator from the tube and put the cap back on the tube. To apply the cream, lie down, put the end of the applicator deep into your vagina and slowly push the plunger all the way in.

Cleaning the applicator

• After use, pull the plunger out of the barrel.
• Wash the plunger and barrel in hand hot, soapy water.
• Do not use detergents. Rinse well with clean water afterwards.
• Do not put the applicator in boiling water. Ovesse is easy to remove with water. Speak to your pharmacist if you experience any difficulties with using the vaginal applicator.

Ovesse is easy to remove with water.

Speak to your pharmacist if you experience any difficulties with using the vaginal applicator.

Please read the Patient Information Leaflet find out what you must do if:

• you use more Ovesse than you should or if you swallow it accidentally
• you forget to use Ovesse
• you stop using Ovesse
• you need to have surgery

Ovesse Cream ingredients

Active ingredient: Estriol. Each gram of cream contains 1 milligram of estriol.

Other ingredients: Chlorhexidine dihydrochloride, octyldodecanol, cetyl palmitate, glycerin, cetyl alcohol, stearyl alcohol, polysorbate 60,sorbitan stearate, lactic acid, sodium hydroxide and purified water.

Ovesse Cream side effects

Stop using this medicine and seek urgent medical attention if you have a serious allergic reaction to Ovesse: A serious allergic reaction may occur only very rarely. Signs may include:

• Suddenly feeling unwell with sweating
• Vomiting
• Difficulty in breathing
• Rapid heartbeat or feeling dizzy.

Stop using Ovesse and seek prompt advice from your doctor if:

• You develop any new vaginal bleeding, spotting or itching
• You have endometriosis and your symptoms have come back
• A vaginal infection develops while you are using Ovesse

Ovesse Cream warnings

• You should not use Ovesse Cream if you have unexplained vaginal bleeding, thickening of the womb lining, liver disease, have ever had breast cancer or other oestrogen-sensitive cancers or have ever had a blood clot or a clotting disorder.
• Speak to your doctor before using Ovesse Cream if you have asthma, epilepsy, diabetes, gallstones, high blood pressure, suffer from migraines or severe headaches, endometriosis, otosclerosis, SLE or fibroids inside your womb.
• You should tell your doctor before using Ovesse Cream if you are currently or have recently stopped using any prescribed or non-prescribed medication.

Ovesse Cream and cancer

It is not known if Ovesse can be safely used in women who had breast cancer in the past.

Ovesse Cream in pregnancy and breastfeeding

Women who are pregnant or breastfeeding should not use Ovesse.

To learn about all the side effects and warnings for Ovesse cream, please see the Patient Information Leaflet that is contained within the product packaging.